Category: Repo

Repo

Rev-erb agonist improvest adverse cardiac remodeling and survival in myocardial infarction through an anti-inflammatory mechanism

http://repository.uhamka.ac.id/id/eprint/17281/

Rev-erb agonist improvest adverse cardiac remodeling and survival in myocardial infarction through an anti-inflammatory mechanism

Endin Nokik Stujanna, Endin

http://repository.uhamka.ac.id/id/eprint/17281/1/reverb%20cek%20similiarity.pdf

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BUDAYA KERJA DOSEN UHAMKA STUDI KORELASIONAL ANTARA PRODUKTIVITAS DAN KOMPENSASI KERJA DENGAN BUDAYA KERJA DOSEN UHAMKA

Post author By Admin Harutya
Post date December 12, 2022
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http://repository.uhamka.ac.id/id/eprint/17449/

BUDAYA KERJA DOSEN UHAMKA STUDI KORELASIONAL ANTARA PRODUKTIVITAS DAN KOMPENSASI KERJA DENGAN BUDAYA KERJA DOSEN UHAMKA

Heri, Totong

Penelitian ini bertujuan untuk mempelajari hubungan antara produktivitas dan kompensasi kerja dengan budaya kerja Dosen, baik secara sendiri-sendiri maupun bersama-sama.
Penelitian dilaksanakan pada Universitas Prof. DR. HAMKA, dengan metode survey. Responden penelitian Dosen berjumlah 175 orang (20 orang untuk uji coba dan 155 orang untuk penelitian), dipilih berdasarkan teknik acak sederhana (simple random sampling). Instrumen menggunakan angket Budaya Kerja Dosen sebagai variabel terikat, sedangkan instrument angket Produktivitas dan Kompensasi kerja sebagai variabel bebas.
Instrumen angket Budaya Kerja Dosen, Produktivitas, dan Kompensasi Kerja divalidasi dengan rumus korelasi product moment, sedangkan relibilitas diukur dengan rumus Alpha Cronbach.
Analisis data menggunakan teknik korelasi dan regresi (sederhana/jamak).
Dari hasil penelitian ditemukan bahwa: (1) terdapat hubungan positif antara Produktivitas dengan Budaya Kerja Dosen, di mana koefisien korelasi ry1 = 0,406; pada taraf signifikansi 0,05 dan persamaan korelasi Y = 151. 092 + 1.003 X1; (2) terdapat hubungan positif antara Kompensasi Kerja dengan Budaya Kerja Dosen, dimana koefisien korelasi ry2 = 0,284 pada taraf signifikansi 0,05 dan persamaan korelasi Y = 151. 092 + 0,992 X2; dan (3) terdapat hubungan positif antara Produktivitas dan Kompensasi Kerja secara bersama-sama dengan Budaya Kerja Dosen, dimana koefisien korelasi jamak Ry.12 = 0,808; pada taraf signifikansi 0,05 dan persamaan regresi jamak Y = -151.092 + 1.003X1 + 0,992X2.
Berdasarkan hasil temuan tersebut, disimpulkan bahwa Budaya Kerja Dosen dapat meningkat apabila Produktivitas dan Kompensasi Kerja juga meningkat. Upaya peningkatan produktivitas dilakukan melalui pelatihan, pendidikan, dan seminar. Sedangkan upaya peningkatan Kompensasi Kerja dilakukan melalui pemberian penghargaan, pengakuan, dan jaminan sosial.

http://repository.uhamka.ac.id/id/eprint/17449/1/TESIS_TOTONG%20HERI.pdf

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Evaluation of morphology and viability of spheroid derived from Insulin-GLase cell line: A model system to understand Type 2 Diabetes Mellitus

http://repository.uhamka.ac.id/id/eprint/17282/

Evaluation of morphology and viability of spheroid derived from Insulin-GLase cell
line: A model system to understand Type 2 Diabetes Mellitus

Sri Suciati Ningsih, Suci

Type 2 Diabetes Mellitus (T2DM) is one of the major health issues in the world. The cellular mechanism of T2DM is still not fully understood.
It could be studied by using spheroid three-dimensional (3D) culture which is considered representative of the in vivo conditions. Several types
of pancreatic β cell lines have been used, one of which is the insulin-GLase (iGL) cell line. This study aims to evaluate the effect of cell density
and incubation time on spheroid morphology and cell viability in order to understand which one can be considered as the best option in studying
T2DM using iGL cell. Spheroid was made by using the Hanging drop method. The variations of initial seeding cells were 50, 100, 200, and 400
cells/µL then incubated for 1, 2, 3, and 4 days. The evaluated parameters in this study are spheroid morphology and cell viability. Spheroid
morphology was observed by using inverted phase contrast microscope integrated with camera (Nikon) and NIS-Elements Analysis D software.
Cell viability was determined by using LUNA-II™ Automated Cell Counter (Logos Biosystem). The result of this study showed that spheroid in
all of the group cell concentration have formed since the first day and its diameter was significantly increased on the following days (p<0,05). The spheroid size was positively correlated with the cell density in group 50-200 cells/µL. A single and stable spheroid morphology was observed in 50-100 cells/µL group. Cell viability in 3D culture system was lower and significantly decreased since day 3 compared to 2D culture (p <0.05; 0.01). In conclusion, spheroid derived from iGL cell line with a stable morphology and good viability could be obtained from a cell concentration of 50-100 cells / µL with two days of incubation. Keywords: iGL, cell density, spheroid, viability http://repository.uhamka.ac.id/id/eprint/17282/1/Evaluation%20of%20morphology%20and%20viability%20of%20spheroid%20derived%20from%20Insulin-GLase%20cell%20line_%20A%20model%20system%20to%20understand%20Type%202%20Diabetes%20Mellitus.pdf Unduh!

Repo

Exercise training reduces ventricular arrhythmias through restoring calcium handling and sympathetic tone in myocardial infarction mice

http://repository.uhamka.ac.id/id/eprint/17283/

Exercise training reduces
ventricular arrhythmias
through restoring calcium
handling and sympathetic tone
in myocardial infarction mice

Endin Nokik Stujanna, Endin

http://repository.uhamka.ac.id/id/eprint/17283/1/Exercise%20training%20reduces%20ventricular%20arrhythmias%20through%20restoring%20calcium%20handling%20and%20sympathetic%20tone%20in%20myocardial%20infarction%20mice.pdf

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